Severe infiltration of the kidneys with ultrasonic abnormalities in acute lymphoblastic leukemia
T. S. Goh, G. W. LeQuesne and K. Y. Wong
A 3-year-old boy with acute lymphoblastic leukemia had enlarged kidneys
with impairment of renal function and hypertension as the presenting
features of relapse. Ultrasound demonstrated multiple nodular areas of
echolucency within enlarged kidneys that reverted to normal when the
patient was in remission but then recurred during relapse. This noninvasive
procedure may be useful in patients with acute lymphoblastic leukemia to
determine the incidence and prognostic significance of renal involvement at
the time of diagnosis, and to follow the course of those who have
demonstrable changes.