Toxic encephalopathy related to antihistamine-barbiturate antiemetic medication
J. F. Schwartz and J. H. Patterson
A toxic encephalopathy characterized by depressed level of consciousness,
marked irritability, and ataxia developed in seven children, 5 years of age
and younger, following administration of an antiemetic combination of
pentobarbital and pyrilamine maleate. Three of the seven patients were
given a dosage of medication and exceeding the manufacture's
recommendation. All seven patients recovered without sequelae.
