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Justen Passwell, MB, ChB, MRCP; Hayim Boichis, MD; Dan Lotan, MD; Rafaele David, MD; Rachel Theodor, MD; Bernard E. Cohen, MB, ChB, FRCPE; Moshe Many, MD, PhD

Am J Dis Child. 1977;131(9):1011-1014.

Abstract
• We report a 14-year-old boy with severe hypertension who was cured by surgical removal of a pheochromocytoma. The tumor was shown biochemically and morphologically to secrete predominantly noradrenaline. The metabolic effects noted in this patient were raised free fatty acid levels and depressed insulin levels, hyperreninemia, hypercalcemia, and hypercalciuria with normal parathyroid function. All these abnormalities returned to normal after removal of the tumor. It is suggested that these effects were mediated via β-adrenergic stimulation of the excess noradrenaline.

(Am J Dis Child 131:1011-1014, 1977)

Author Affiliations
From the Departments of Pediatrics B (Drs Passwell, Boichis, Lotan, Theodor, Cohen), Pathology (Dr David), and Urology (Dr Many), The Chaim Sheba Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Hashomer, Israel. Dr Passwell is now with The Children's Hospital Medical Center, Boston.

Footnotes
Reprint requests to Pediatric Renal Unit, The Chaim Sheba Medical Center, Tel-Hashomer, Israel (Dr Boichis).

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