Beckwith-Wiedemann syndrome in a mother and her son

E. Ben-Galim, E. Gross-Kieselstein and A. Abrahamov

The Beckwith-Wiedemann syndrome--exomphalos, macroglossia and gigantism--occurred in a mother and her son. The clinical and metabolic features of this syndrome are described. We believe this is the first report of this syndrome affecting a mother and her son. An autosomal dominant pattern of inheritance is suggested.