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Arun K. Pramanik, MD; Geoffrey Altshuler, MB, BS; Irwin J. Light, MD; James M. Sutherland, MD

Am J Dis Child. 1977;131(6):672-674.

Abstract
• Three fatal cases of prune-belly syndrome were associated with nonrenal features of Potter syndrome. The abdominal muscle hypoplasia is thought to be a result of large kidneys compressing the developing abdominal musculature during a critical phase of fetal development. Thus, Potter syndrome and prune-belly syndrome may coexist when nonfunctioning large kidneys result in oligohydramnios. A teratogenic role of cytomegalovirus inclusion disease and other viruses is possible in the pathogenesis of these syndromes.

(Am J Dis Child 131:672-674, 1977)

Author Affiliations
From the Departments of Pediatrics, Obstetrics (Dr Light and Sutherland), and Pathology (Dr Altshuler) at the University of Cincinnati College of Medicine, the Crosley Memorial Nursery at the Cincinnati General Hospital; and the Fels Division of Pediatric Research, Fels Research Institute for Study of Human Development, Yellow Springs, Ohio. Dr Altshuler is now with the Department of Pathology, University of Oklahoma.

Footnotes
Reprint requests to University of Cincinnati, College of Medicine, 231 Bethesda Ave, Cincinnati, OH 45267 (Dr Light).

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