Bordetella parapertussis. Recent experience and a review of the literature
C. C. Linnemann and E. B. Perry
During 1974, eight of 37 (22%) Bordetella organisms isolated from patients
in Cincinnate were Bordetella parapertussis. This is in contrast to other
experience in the United States where parapertussis has comprised less
than5% of the Bordetella species isolated and suggest that B parapertussis
infection may be more common in this country than generally recognized. The
failure to appreciate the presence of this infection may result from the
lack of cultures taken from children with mild disease and the failure
todistinguish B parapertussis from B pertussis. Ccultures were obtained
from family members of three of the children with B parapertussis, and B
pertussis was isolated from members of two families, including the mother
and sister of a child who died of pneumonia and encephalopathy. These cases
suggest that patients with severe disease associated with B parapertussis
should be carefully evaluated for the possibility of dual infection caused
by b pertussis.
Co-infection with two different strains of Bordetella pertussis in an infant
Cassiday et al.
J Med Microbiol 2008;57:388-391.
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Molecular Pathogenesis, Epidemiology, and Clinical Manifestations of Respiratory Infections Due to Bordetella pertussis and Other Bordetella Subspecies
Mattoo and Cherry
Clin. Microbiol. Rev. 2005;18:326-382.
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Bordetella Species Are Distinguished by Patterns of Substantial Gene Loss and Host Adaptation
Cummings et al.
J. Bacteriol. 2004;186:1484-1492.
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Role of Antibodies against Bordetella pertussis Virulence Factors in Adherence of Bordetella pertussis and Bordetella parapertussis to Human Bronchial Epithelial cells
van den Berg et al.
Infect. Immun. 1999;67:1050-1055.
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Pertussis Encephalopathy With High Cerebrospinal Fluid Antibody Titers to Pertussis Toxin and Filamentous Hemagglutinin
Grant et al.
Pediatrics 1998;102:986-989.
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Bordetella parapertussis Infection in Children: Epidemiology, Clinical Symptoms, and Molecular Characteristics of Isolates
Mastrantonio et al.
J. Clin. Microbiol. 1998;36:999-1002.
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A Comparative Efficacy Trial in Germany in Infants Who Received Either the Lederle/Takeda Acellular Pertussis Component DTP (DTaP) Vaccine, the Lederle Whole-Cell Component DTP Vaccine, or DT Vaccine
Stehr et al.
Pediatrics 1998;101:1-11.
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