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Echocardiography in Cystic Fibrosis
Michael Gewitz, MD;
Eshagh Eshaghpour, MD;
Douglas S. Holsclaw, MD;
Howard A. Miller, MD;
Nobuyoshi Kawai, MD
Am J Dis Child. 1977;131(3):275-280.
Abstract
• Echocardiograms were obtained for 25 patients with cystic fibrosis (CF) and 20 controls to evaluate this technique as a means of assessment of right ventricular changes in patients with CF. Right ventricular anterior wall thickness per square meter of body surface (RVAW/sq m) and right ventricular internal dimension per square meter of body surface (RVID/sq m) were compared with other techniques for detection of cor pulmonale. Significant correlations existed between both RVAW/sq m and RVID/sq m and the forced vital capacity, forced expiratory volume in one second, midmaximal expiratory flow rate, clinical score of severity of disease, and roentgenographic score of pulmonary involvement. The RVAW/sq m was slightly more sensitive than RVID/sq m; RVAW/sq m thickness on echocardiogram in vivo compared well with actual measurements at autopsy in five patients. No correlations were found between echocardiography and electrocardiograms, vectorcardiograms, thoracic index, or cardiothoracic ratio.
(Am J Dis Child 131:275-280, 1977)
Author Affiliations
From the Departments of Pediatrics and Medicine, and the Divisions of Cardiology and Pediatric Pulmonary Diseases, Hahnemann Medical College and Hospital, Philadelphia.
Footnotes
Read before the annual meeting of the American Heart Association, Dallas, Nov 12, 1974.
Reprint requests to Department of Pediatrics, Hahnemann Medical College and Hospital, 230 N Broad St, Philadelphia, PA 19102 (Dr Eshaghpour).
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