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Diabetes Mellitus, Islet-Cell Antibodies, and HLA-B8 in a Patient With Systemic Lupus Erythematosus
Lee S. Fruman, MD
Am J Dis Child. 1977;131(11):1252-1254.
Abstract
• Evidence that autoimmune mechanisms may provide a possible explanation for the occurrence of some types of diabetes mellitus has included the clinical association of diabetes with other autoimmune conditions and the serologic demonstration of organ-specific antibodies. This article reports the case of a patient with systemic lupus erythematosus accompanied by diabetes and the presence of antibodies to pancreatic islet cells. This represents further evidence that autoimmune activity may play a role in the etiology of diabetes mellitus, which is especially interesting in light of recent HLA antigen studies that show a possible genetic link between the two diseases.
(Am J Dis Child 131:1252-1254, 1977)
Author Affiliations
From the Department of Pediatrics, William Beaumont Hospital, Royal Oak, Mich.
Footnotes
Dr. Fruman is now with the Division of Emergency Medicine, Henry Ford Hospital, West Bloomfield, Mich.
Reprint requests to 30670 Rushmore Circle, Franklin, MI 48025 (Dr Fruman).
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