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Arteriovenous Malformation of the Vein of GalenTreatment in a Neonate
David G. Watson, MD;
Robert R. Smith, MD;
Alfred W. Brann, Jr, MD
Am J Dis Child. 1976;130(5):520-525.
Abstract
Heart failure in a 2-day-old infant was not readily explained by clinical examination. Cardiac catheterization suggested an intracranial arteriovenous (AV) fistula, and cerebral arteriography showed a malformation of the vein of Galen. The major feeding arteries were surgically obliterated. At age 27 months, the boy has normal mentation but moderate left hemiparesis. Review of the literature disclosed 39 other infants with AV malformations of the vein of Galen producing heart failure before age 3 months. Most of them were boys, and had cyanosis, a systolic murmur, cranial bruit, cardiomegaly, and right ventricular hypertrophy. Only three of the 13 who had surgery for their malformation survived. Removal of the malformation is difficult; obliteration of the nutrient vessels, using the operating microscope, is the currently accepted treatment.
(Am J Dis Child 130:520-525, 1976)
Author Affiliations
From the departments of pediatrics (Drs Watson and Brann) and neurosurgery (Dr Smith), University of Mississippi School of Medicine, Jackson.
Footnotes
Received for publication Dec 11,1973; accepted June 10, 1975.
Reprint requests to Department of Pediatrics, University Medical Center, 2500 N State St, Jackson, MS 39216 (Dr Watson).
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