Growth failure with pericardial constriction. The syndrome of mulibrey nanism
M. L. Voorhess, G. S. Husson and M. S. Blackman
The features of the syndrome of mulibrey nanism, an autosomal recessive
disorder of unknown pathogenesis, include severe growth failure, yellow
pigmentation of the retina, evidence of pericardial constriction, J-shaped
sella turcica, and fibrous dysplasia of bones. To date, 24 individuals from
Finland and a boy from Egypt have been reported with the syndrome. The
patient reviewed in this article is the first known affected child from the
United States. It is important that physicians look for this disorder in
children with severe growth failure and hepatomegaly because of the
potential seriousness of undetected pericardial constriction.
