 |
|
Powassan Virus InfectionA Report of Three Human Cases of Encephalitis
Ross Smith, MD;
John P. Woodall, PhD;
Elinor Whitney, MS;
Rudolf Deibel, MD;
Michael A. Gross, MD;
Victoria Smith, MD;
Thomas F. Bast, PhD
Am J Dis Child. 1974;127(5):691-693.
Abstract
Powassan virus infection was confirmed serologically in three children with a clinical diagnosis of encephalitis (two) or meningoencephalitis (one). One child had a paresis and recovered but is left with spasticity in one leg; the other two children had no apparent sequelae. Only one patient had a history of a recent tick bite. Powassan hemagglutination-inhibiting and neutralizing antibodies were detected early after onset of illness. Complement-fixing antibody appeared later. Two of the patients also had virological evidence of subsequent, but closely spaced, echovirus infection. A synergistic effect may be of importance in encephalitis associated with Powassan infection. The absence of tick bites in two of the children suggests that other ways of transmission of Powassan virus must be considered.
Author Affiliations
Albany, NY
From the Division of Laboratories and Research (Drs. R. Smith, Woodall, Deibel, and Miss Whitney) and the Bureau of Acute Communicable Disease Control (Drs. Gross, V. Smith, and Bast), New York State Department of Health, Albany.
Footnotes
Received for publication Nov 19, 1973; accepted Dec 26.
Reprint requests to Division of Laboratories and Research, New York State Department of Health, New Scotland Ave, Albany, NY 12201 (Dr. Deibel).
 CiteULike  Connotea  Delicious  Digg  Facebook  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Phylogeny of North American Powassan virus
Ebel et al.
J. Gen. Virol. 2001;82:1657-1665.
ABSTRACT
| FULL TEXT
Powassan encephalitis: a case report with neuropathology and literature review
Gholam et al.
CMAJ 1999;161:1419-1422.
FULL TEXT
Powassan Virus Encephalitis Resembling Herpes Simplex Encephalitis
Embil et al.
Arch Intern Med 1983;143:341-343.
ABSTRACT
|
