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Julius Landwirth, MD; Alexander Berger, MD

Am J Dis Child. 1973;126(6):851-853.

Abstract
A 13-year-old boy with Klinefelter syndrome who developed systemic lupus erythematosus is presented. To our knowledge, this is the fourth instance of this combination reported in the literature. The association of chromosomal anomalies and homologous autoantibodies in various clinical contexts may suggest an underlying relationship between these two phenomena.

Author Affiliations
Bridgeport, Conn

From the Department of Pediatrics (Dr. Landwirth) and Family Practice Medicine Program (Dr. Berger), Bridgeport Hospital, Bridgeport, Conn, and Yale University School of Medicine, New Haven, Conn.

Footnotes
Received for publication June 1, 1973; accepted Aug 3, 1973.

Reprint requests to Department of Pediatrics, Bridgeport Hospital, 267 Grant St, Bridgeport, CT 06602 (Dr. Landwirth).

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