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45, X Chromosome Abnormality in the Offspring of a Narcotic Addict
Theodore Kushnick, MD;
Marcy Robinson, MS;
Carrie Tsao
Am J Dis Child. 1972;124(5):772-773.
Abstract
During a cytogenetic investigation of adult narcotic addicts and their newborn offspring, a female infant with a 45,X karyotype was born to a woman who used heroin and cocaine. The baby had multiple features consistent with the Turner's syndrome phenotype, with the additional findings of bilaterally absent fifth toes. This infant was one of 30 offspring of drug addicts, and while this case might represent a fortuitous circumstance, the possibility of increased incidence of newborn chromosomal aberration with parental drug addiction must be considered.
Author Affiliations
Newark, NJ
From the departments of pediatrics (Dr. Kushnick) and preventive medicine (Ms. Robinson and Ms. Tsao), division of drug abuse, New Jersey Medical School, Newark.
Footnotes
Received for publication June 15, 1972; accepted July 31.
Reprint requests to Department of Pediatrics, New Jersey Medical School, 100 Bergen St, Newark 07103 (Dr. Kushnick).
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