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Arachnodactyly (Marfan's Syndrome) With XYY Karyotype
Peter St. J. Dignan, MD;
Kenneth Kreines, MD;
Shirley Soukup, PhD;
Josef Warkany, MD
Am J Dis Child. 1972;124(2):266-270.
Abstract
The chromosome analysis for an unusually tall 13-year-old boy with long slender limbs, clawed toes, pigeon chest, myopia with corectopia, and behavior problems showed a 47, XYY constitution. His dermatoglyphics are characterized by an extremely low ridge count. The diagnosis of Marfan's syndrome is considered.
Author Affiliations
Cincinnati
From the University Affiliated Program for the Mentally Retarded, the Department of Pediatrics of the University of Cincinnati, College of Medicine (Dr. Dignan); the Department of Internal Medicine, Metabolism Division, University Medical Center, Cincinnati (Dr. Kreines); and the Children's Hospital Research Foundation (Drs. Soukup and Warkany).
Footnotes
Received for publication Jan 4, 1972; accepted April 17.
Reprint requests to the Hamilton County Diagnostic Clinic, 295 Erkenbrecher Ave, Cincinnati 45229 (Dr. Dignan).
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