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A New Experimental Model of Polycystic KidneysSimilarity to a Human Variety
John D. Vlachos, MD
Am J Dis Child. 1972;123(2):118-120.
Abstract
The production of polycystic renal disease in newborn rabbits by the use of a long-acting corticosteroid, fluprednisolone (Predef 2x [Greece]; Alphadrol; comparable US product) as reported by Perey et al has been confirmed and extended. Rabbits followed up to 3 months of age show disappearance of the cysts. Comparison with "glomerular" type human polycystic kidney shows important similarities.
Author Affiliations
Athens, Greece
From the Department of Pathology, Evangelismos Medical Center, Athens, Greece.
Footnotes
Received for publication March 9, 1971; accepted Oct 7.
Reprint requests to Department of Pathology, Evangelismos Medical Center, Athens, Greece (Dr. Vlachos).
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