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Immunofluorescent Studies

Samuel F. Bean, MD; LCDR Robert E. Jordon, USNR; Richard K. Winkelmann, MD; Robert A. Good, MD

Am J Dis Child. 1971;122(2):137-141.

Abstract
The chronic nonhereditary blistering diseases (pemphigus, bullous pemphigoid, dermatitis herpetiformis) have been reported or observed in children, and examples have been studied immunologically. Fluorescent staining has revealed characteristic immunologic changes in children with pemphigus and with bullous pemphigoid; no immunologic findings have been reported in patients with papulovesicular dermatitis herpetiformis or so-called bullous pemphigoid of childhood. This last entity, initially thought to represent bullous pemphigoid or a bullous form of dermatitis herpetiformis, may best be separated from both of these diseases, and better referred to as "benign chronic bullous dermatosis of childhood."

Author Affiliations
Minneapolis

From the departments of dermatology (Dr. Bean), pediatrics, microbiology, and pathology (Dr. Good), University of Minnesota, Minneapolis; and the Department of Dermatology, Mayo Clinic, Rochester, Minn (Dr. Winkelmann). Dr. Bean is now with the Diagnostic Clinic of Houston.

Footnotes
Received for publication Nov 19, 1970; accepted March 8, 1971.

Reprint requests to Diagnostic Clinic of Houston, 6448 Fannin, Houston 77025 (Dr. Bean).

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